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half-dozen Integumentary System

  • Identify the anatomy of the integumentary organization
  • Depict the main functions of the integumentary organization
  • Spell the integumentary arrangement medical terms and employ correct abbreviations
  • Identify the medical specialties associated with the integumentary system
  • Explore common diseases, disorders, and procedures related to the integumentary organisation

Integumentary System Discussion Parts

Click on prefixes, combining forms, and suffixes to reveal a list of word parts to memorize for the Integumentary Organisation.

Introduction to the Integumentary Arrangement

The integumentary system refers to the skin and its accompaniment structures. In the adult human torso, the peel makes up about 16 percent of body weight and covers an area of i.5 to ii g2.

In fact, the skin and accessory structures are the largest organ system in the human torso. The skin protects your inner organs and information technology is in demand of daily intendance and protection to maintain its health.

Watch this video:

Media 6.1. The Integumentary Arrangement, Role ane – Skin Deep: Crash Grade A&P #6 [Video]. Copyright 2015 by CrashCourse.

Practice integumentary system medical terms.

Anatomy (Structures) of the Integumentary System

The peel and its accompaniment structures make upwards the integumentary system, which provides the trunk with overall protection. The skin is fabricated of multiple layers of cells and tissues, which are held to underlying structures by connective tissue. The deeper layer of pare is well . It also has numerous sensory, and and nervus fibers ensuring communication to and from the brain.

The skin is composed of ii principal layers:

  1. The
  2. The
    1. Below the dermis lies the
Layers of the skin. Image description available.
Figure six.1 Layers of Skin. From Betts, et al., 2013. Licensed nether CC BY four.0. [Epitome description.]
  • On the diagram above find the two layers of the skin; epidermis and dermis.
  • The literal breakdown for hypodermis is beneath the dermis. On the diagram in a higher place where can you locate it?
  • Tin can you find a pilus follicle , hair root and hair shaft?
  • Proceed reading to find out what the arrector pili muscle does when you lot are frightened.

​​​​Epidermis

The is composed of keratinized, stratified squamous epithelium. It is fabricated of four or five layers of epithelial cells, depending on its location in the body. It is .

  • Thin skin has iv layers of cells. From deep to superficial, these layers are the , stratum spinosum, stratum granulosum, and stratum corneum. Nearly of the skin tin can exist classified as thin peel.
  • Thick skin is found only on the palms of the hands and the soles of the feet. It has a fifth layer, called the stratum lucidum, located between the stratum corneum and the stratum granulosum (meet Figure six.ii).
Thin skin versus thick skin in photographs. Image description available.
Figure 6.2 Thin Skin versus Thick Peel. These slides show cross-sections of the epidermis and dermis of (a) thin and (b) thick peel. Notation the significant difference in the thickness of the epithelial layer of the thick skin. From top, LM × 40, LM × 40. (Micrographs provided by the Regents of University of Michigan Medical Schoolhouse © 2012). From Betts, et al., 2013. Licensed under CC BY 4.0. [Paradigm clarification.]

The cells in all of the layers except the stratum basale are called . Keratin is an intracellular fibrous protein that gives hair, nails, and skin their hardness and water-resistant properties. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from the deeper layers (see Figure vi.three).

The epidermis. Image description available.
Figure six.iii Epidermis. The epidermis is epithelium composed of multiple layers of cells. The basal layer consists of cuboidal cells, whereas the outer layers are squamous, keratinized cells, and so the whole epithelium is often described as being keratinized stratified squamous epithelium. LM × 40. (Micrograph provided by the Regents of University of Michigan Medical School © 2012). From Betts, et al., 2013. Licensed under CC Past 4.0. [Image clarification.]

Dermis

The dermis contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers (papillary layer and reticular layer) of connective tissue that compose an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts (come across Figure vi.four).
Layers of the dermis. Image description available.
Figure 6.4 Layers of the Dermis. This stained slide shows the 2 components of the dermis—the papillary layer and the reticular layer. Both are made of connective tissue with fibers of collagen extending from 1 to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis vest to the papillary layer, whereas the dumbo collagen fiber bundles below belong to the reticular layer. LM × 10. (credit: modification of piece of work by "kilbad"/Wikimedia Commons).  From Betts, et al., 2013. Licensed nether CC By 4.0. [Image description.]

Papillary Layer

The papillary layer is made of loose, areolar connective tissue, which means the collagen and elastin fibers of this layer course a loose mesh. This superficial layer of the dermis projects into the stratum basale of the epidermis to form finger-like dermal papillae (see Effigy 6.iv). Within the papillary layer are fibroblasts, a minor number , and an affluence of small blood vessels. In improver, the papillary layer contains , that assistance fight bacteria or other infections that have breached the pare. This layer also contains lymphatic capillaries, nerve fibers, and  .

Reticular Layer

Underlying the papillary layer is the much thicker reticular layer, composed of dumbo, irregular connective tissue. This layer is well and has a rich sensory and nerve supply. The reticular layer appears due to a tight meshwork of fibers. Elastin fibers provide some elasticity to the skin, enabling movement. Collagen fibers provide construction and tensile strength, with strands of collagen extending into both the papillary layer and the hypodermis. In add-on, collagen binds water to keep the skin hydrated. Collagen injections and Retin-A creams help restore skin turgor by either introducing collagen externally or stimulating claret period and repair of the dermis, respectively.

Hypodermis

The serves to connect the skin to the underlying of the bones and muscles. It is not strictly a part of the skin, although the edge between the and can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and tissue, which functions as a mode of fat storage and provides insulation and cushioning for the integument.

Practice labeling the layers of the skin.

Physiology (Part) of the Integumentary Arrangement

The pare and accompaniment structures perform a diversity of essential functions, such as protecting the torso from invasion past microorganisms, chemicals, and other environmental factors; preventing dehydration; acting as a sensory organ; modulating torso temperature and electrolyte balance; and synthesizing vitamin D. The underlying hypodermis has important roles in storing fats, forming a "cushion" over underlying structures, and providing insulation from cold temperatures.

Protection

The skin protects the body from air current, water, and UV sunlight. It acts as a protective barrier against water loss and information technology too is the first line of defence against abrasive activeness such as dust, microbes, or harmful chemicals. Sweat excreted from sweat glands deters microbes from over-colonizing the skin surface by generating dermicidin, which has antibody backdrop.

Sensory Office

The skin acts as a sense organ because the epidermis, dermis, and the hypodermis contain specialized sensory nerve structures that detect touch, surface temperature, and pain. These receptors are more concentrated on the tips of the fingers, which are well-nigh sensitive to touch, especially the , which responds to low-cal touch, and the , which responds to vibration. Merkel cells, seen scattered in the stratum basale, are also touch receptors. In addition to these specialized receptors, there are sensory fretfulness connected to each hair follicle, pain and temperature receptors scattered throughout the skin, and motor nerves innervate the arrector pili muscles and glands. This rich innervation helps the states sense our surroundings and react accordingly,

Thermoregulation

The integumentary organization helps regulate trunk temperature through its tight association with the . The sympathetic nervous system is continuously monitoring torso temperature and initiating appropriate motor responses.

  1.  When the body becomes warm sweat glands, accompaniment structures to the peel, secrete h2o, table salt, and other substances to absurd the body.
    1. Even when the trunk does not announced to exist noticeably sweating, approximately 500 mL of sweat are secreted a day.
  2. If the torso becomes excessively warm due to high temperatures, vigorous activity, or a combination of the two, sweat glands will exist stimulated by the sympathetic nervous system to produce large amounts of sweat.
    1. When the sweat evaporates from the skin surface, the body is cooled every bit body rut is prodigal.
    2. In add-on to sweating, arterioles in the dermis dilate so that excess rut carried past the blood can dissipate through the skin and into the surrounding environment (Figure 2b).
    3. This accounts for the skin redness that many people experience when exercising.
  3. When body temperatures drop, the arterioles constrict to minimize oestrus loss, especially in the ends of the digits and tip of the nose.
    1. This reduced apportionment tin can result in the skin taking on a whitish hue.
    2. Although the temperature of the skin drops as a event, passive heat loss is prevented, and internal organs and structures remain warm.
    3. If the temperature of the pare drops too much (such as ecology temperatures below freezing), the conservation of body core heat tin can consequence .
Thermoregulation. Image description available.
Figure 6.5 Thermoregulation. During strenuous physical activities, such as skiing (a) or running (c), the dermal blood vessels dilate and sweat secretion increases (b). These mechanisms prevent the body from overheating. In contrast, the dermal blood vessels tuck to minimize heat loss in response to depression temperatures (b). (credit a: "Trysil"/flickr; credit c: Ralph Daily). From Betts, et al., 2013. Licensed under CC BY iv.0. [Epitome description.]

Can you describe the thermoregulation process between the integumentary system and the sympathetic organization?

  • When trunk temperature is too warm.
  • When body temperature is too common cold.

Vitamin D Synthesis

The epidermal layer of human peel synthesizes Vitamin D when exposed to UV radiation. In the presence of sunlight, a form of Vitamin Dthree chosen cholecalciferol is synthesized from a derivative of the steroid cholesterol in the skin. The liver converts cholecalciferol to calcidiol, which is and then converted to calcitriol (the active chemical class of the vitamin) in the kidneys.

  • Vitamin D is essential for normal absorption of calcium and phosphorous, which are required for healthy bones.
  • The absence of sun exposure can atomic number 82 to a lack of vitamin D in the body, in children this can cause .  Vitamin D deficiency in elderly individuals may pb to .
  • In present day society, Vitamin D is added as a supplement to many foods, including milk and orange juice, compensating for the need for sun exposure. In improver to its essential office in bone wellness, Vitamin D is essential for general immunity confronting bacterial, viral, and fungal infections.

Watch this video:

Media 6.2. The Integumentary System, Role 2 – Pare Deeper: Crash Grade A&P #7 [Online video]. Copyright 2015 by CrashCourse.

Accompaniment Structures

Accessory structures of the skin include hair, nails, sweat glands, and sebaceous glands. These structures embryologically originate from the epidermis and can extend downward through the dermis into the .

Hair

Hair is a keratinous filament growing out of the . It is primarily made of dead, keratinized cells. Strands of hair originate in an epidermal penetration of the dermis called the hair follicle. The hair shaft is the role of the hair not anchored to the follicle, and much of this is exposed at the peel'due south surface. The rest of the hair, which is anchored in the follicle, lies below the surface of the peel and is referred to as the hair root. The hair root ends deep in the dermis at the hair seedling, and includes a layer of mitotically active basal cells called the hair matrix. The hair bulb surrounds the hair papilla, which is fabricated of connective tissue and contains claret capillaries and nerve endings from the dermis (see Figure 6.6).

Cross section of a hair follicle. Image description available.
Effigy 6.6 Hair. Hair follicles originate in the epidermis and have many different parts. From Betts, et al., 2013. Licensed under CC BY four.0. [Paradigm clarification.]

Hair Office

Pilus serves a diverseness of functions, including protection, sensory input, thermoregulation, and communication. For example:

  • Pilus on the head protects the skull from the sun.
  • Hair in the nose and ears, and around the eyes (eyelashes) defends the body by trapping and excluding dust particles that may contain allergens and microbes.
  • Hair of the eyebrows prevents sweat and other particles from dripping into and bothering the eyes.

Hair also has a sensory function due to sensory innervation past a hair root plexus surrounding the base of each hair follicle. Pilus is extremely sensitive to air motility or other disturbances in the environment, much more and then than the skin surface. This characteristic is also useful for the detection of the presence of insects or other potentially damaging substances on the skin surface.

Each hair root is connected to a smoothen muscle chosen the arrector pili that contracts in response to nerve signals from the sympathetic nervous organization, making the external hair shaft "stand upward." The primary purpose for this is to trap a layer of air to add together insulation. This is visible in humans as goose bumps and even more than obvious in animals, such as when a frightened true cat raises its fur. Of course, this is much more obvious in organisms with a heavier coat than most humans, such as dogs and cats.

Hair Growth, Loss and Colour

Hair grows and is somewhen shed and replaced by new hair.  Hair typically grows at the rate of 0.3 mm per day. On boilerplate, 50 hairs are lost and replaced per day. Hair loss occurs if at that place is more hair shed than what is replaced and can happen due to hormonal or dietary changes. Hair loss can also upshot from the aging process, or the influence of hormones. Like to the peel, pilus gets its colour from the pigment melanin, produced by in the hair papilla. Different pilus color results from differences in the blazon of melanin. As a person ages, the melanin production decreases, and pilus tends to lose its colour and becomes grey and/or white.

Nails

The nail bed is a specialized construction of the epidermis that is found at the tips of our fingers and toes. The smash torso is formed on the nail bed, and protects the tips of our fingers and toes as they are the farthest extremities and the parts of the body that feel the maximum mechanical stress (see Figure 6.7). The nail trunk forms a back-support for picking upwardly modest objects with the fingers. The boom body is composed of densely packed expressionless .

The epidermis in this part of the body has evolved a specialized structure upon which nails can form. The blast trunk forms at the nail root, which has a matrix of proliferating cells from the stratum basale that enables the nail to abound continuously. The lateral boom fold overlaps the nail on the sides, helping to anchor the nail torso. The nail fold that meets the proximal end of the nail body forms the blast cuticle, also chosen the eponychium.

The nail bed is rich in blood vessels, making it announced pink, except at the base, where a thick layer of epithelium over the nail matrix forms a crescent-shaped region called the lunula (the "petty moon"). The area beneath the free border of the nail, furthest from the cuticle, is called the hyponychium. Information technology consists of a thickened layer of stratum corneum.

Anatomy of the fingernail. Image description available.
Figure 6.seven Nails. The nail is an accessory structure of the integumentary system. From Betts, et al., 2013. Licensed under CC By iv.0. [Paradigm description.]

Sweat Glands

Sudoriferous Glands

When the body becomes warm, sudoriferous glands produce sweat to cool the body. Sweat glands develop from epidermal projections into the dermis and are classified as merocrine glands; that is, the secretions are excreted past through a duct without affecting the cells of the gland. In that location are two types of sweat glands, each secreting slightly different products.

An eccrine sweat gland is type of gland that produces a hypotonic sweat for thermoregulation equally described previously. These glands are establish all over the skin's surface, only are peculiarly abundant on the palms of the hand, the soles of the feet, and the brow (Effigy vi.8). They are coiled glands lying deep in the dermis, with the duct rising up to a pore on the peel surface, where the sweat is released. This type of sweat, released by , is hypotonic and composed more often than not of water, with some salt, antibodies, traces of metabolic waste matter, and dermicidin, an antimicrobial peptide. Eccrine glands are a primary component of thermoregulation in humans and thus help to maintain .

Eccrine sweat gland. Image description available.
Figure 6.8 Eccrine Gland. Eccrine glands are coiled glands in the dermis that release sweat that is mostly h2o. From Betts, et al., 2013. Licensed under CC By 4.0. [Image clarification.]

An apocrine sweat gland is usually associated with hair follicles in densely hairy areas, such every bit armpits and genital regions. Apocrine sweat glands are larger than eccrine sweat glands and lie deeper in the dermis, sometimes even reaching the hypodermis, with the duct usually emptying into the hair follicle. In addition to water and salts, apocrine sweat includes organic compounds that make the sweat thicker and subject to bacterial decomposition and subsequent smell. The release of this sweat is under both nervous and hormonal control, and plays a role in the poorly understood man pheromone response. Nigh commercial antiperspirants utilize an aluminum-based chemical compound as their primary agile ingredient to finish sweat. When the antiperspirant enters the sweat gland duct, the aluminum-based compounds precipitate due to a modify in pH and course a physical block in the duct, which prevents sweat from coming out of the pore.

Sebaceous Glands

A sebaceous gland is a type of oil gland that is institute all over the torso and helps to lubricate and waterproof the skin and hair. Most sebaceous glands are associated with pilus follicles. They generate and excrete sebum, a mixture of lipids, onto the peel surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable. The fatty acids of sebum as well have antibacterial properties, and prevent h2o loss from the skin in low-humidity environments. The secretion of sebum is stimulated by hormones, many of which practise not become agile until puberty. Thus, sebaceous glands are relatively inactive during childhood.

Words not Easily Broken into Word Parts

Common Integumentary Organization Abbreviations

Many terms and phrases related to the integumentary system are abbreviated.  Learn these common abbreviations past expanding the list below.

Changes Due to Aging

All systems in the trunk accumulate subtle and some not-so-subtle changes as a person ages. Amongst these changes are reductions in cell division, metabolic activity, blood circulation, hormonal levels, and muscle forcefulness (see Figure 6.ix). In the skin, these changes are reflected in decreased mitosis in the stratum basale, leading to a thinner epidermis. The dermis, which is responsible for the elasticity and resilience of the skin, exhibits a reduced ability to regenerate, which leads to slower wound healing. The hypodermis, with its fat stores, loses structure due to the reduction and redistribution of fat, which in plough contributes to the thinning and sagging of pare.

Young and older woman on the telephone. Image description available.
Figure 6.9 Crumbling. Generally, skin, especially on the face and hands, starts to display the first noticeable signs of aging, as it loses its elasticity over time. (credit: Janet Ramsden). From Betts, et al., 2013. Licensed under CC BY 4.0. [Epitome description.]

The accessory structures also have lowered action, generating thinner hair and nails, and reduced amounts of sebum and sweat. A reduced sweating ability can crusade some elderly to be intolerant to farthermost rut. Other cells in the pare, such every bit and cells, also go less agile, leading to a paler peel tone and lowered immunity. Wrinkling of the skin occurs due to breakup of its structure, which results from decreased collagen and elastin product in the dermis, weakening of muscles lying under the peel, and the inability of the skin to retain acceptable moisture.

Disease and Disorders

The integumentary organization is susceptible to a variety of diseases, disorders, and injuries. These range from annoying only relatively benign bacterial or fungal infections that are categorized as disorders, to peel cancer and severe burns, which tin can be fatal. In this section, you will learn several of the most common pare weather condition.

I of the most talked about diseases is skin . Virtually cancers are identified by the organ or tissue in which the cancer originates. One common form of cancer is skin cancer.

In general, cancers result from an accumulation of DNA mutations. These mutations can outcome in cell populations that do not dice when they should and uncontrolled cell proliferation that leads to tumors. Although many tumors are , some . Cancers are characterized past their ability to metastasize.

Dominicus Impairment

It requires nearly 10 days subsequently initial dominicus exposure for melanin synthesis to peak, which is why pale-skinned individuals tend to endure sunburns of the epidermis initially. Nighttime-skinned individuals can as well get sunburns, but are more protected than are pale-skinned individuals. Too much lord's day exposure can eventually atomic number 82 to wrinkling due to the destruction of the cellular structure of the skin, and in astringent cases, can cause sufficient DNA impairment to result in peel cancer. When at that place is an irregular accumulation of melanocytes in the skin, freckles announced. Moles are larger masses of melanocytes, and although nearly are beneficial, they should be monitored for changes that might indicate the presence of cancer (see Figure six.ten).

Five photos of moles. Image description available.
Figure vi.ten Moles. Moles range from benign accumulations of melanocytes to melanomas. These structures populate the mural of our skin. (credit: the National Cancer Plant). From Betts, et al., 2013. Licensed under CC BY 4.0. [Image description.]

Basal Jail cell Carcinoma (BCC)

Image of basal cell carcinoma
Effigy 6.11 Basal Cell Carcinoma. Basal cell carcinoma can take several different forms. Similar to other forms of skin cancer, information technology is readily cured if defenseless early and treated. (credit: John Hendrix, Medico). From Betts, et al., 2013. Licensed under CC BY 4.0.

Basal cell carcinoma is a form of cancer that affects the mitotically agile stem cells in the stratum basale of the epidermis. It is the most common of all cancers that occur in the United States and is frequently found on the head, neck, arms, and back, which are are as that are most susceptible to long-term lord's day exposure. Although UV rays are the main culprit, exposure to other agents, such as radiation and arsenic, can also lead to this type of cancer. Wounds on the peel due to open up sores, tattoos, burns, etc. may be predisposing factors. Basal cell carcinomas start in the stratum basale and usually spread along this boundary. At some point, they brainstorm to abound toward the surface and become an uneven patch, bump, growth, or scar on the skin surface (meet Figure half dozen.11). Similar most cancers, basal cell carcinomas respond all-time to treatment when caught early. Treatment options include surgery, freezing (cryosurgery), and topical ointments.

Squamous Cell Carcinoma (SCC)

Image of squamous cell carcinoma on a person's nose
Figure 6.12 Squamous Cell  Carcinoma Squamous cell carcinoma presents here equally a lesion on a nose. (credit: the National Cancer Plant). From Betts, et al., 2013. Licensed under CC Past four.0.

Squamous cell carcinoma is a cancer that affects the keratinocytes of the stratum spinosum and presents as lesions ordinarily found on the scalp, ears, and hands (see Figure 6.12). It is the 2d most mutual pare cancer. The American Cancer Society reports that two of 10 skin cancers are squamous cell carcinomas, and it is more aggressive than basal prison cell carcinoma. If non removed, these carcinomas can . Surgery and radiation are used to cure squamous cell carcinoma.

Melanoma

Image of a melanoma
Figure 6.xiii Melanoma. Melanomas typically present equally large brown or blackness patches with uneven borders and a raised surface. (credit: the National Cancer Institute). From Betts, et al., 2013. Licensed under CC By 4.0.

A melanoma is a cancer characterized by the uncontrolled growth of melanocytes, the pigment-producing cells in the epidermis. Typically, a melanoma develops from a mole. Information technology is the near fatal of all skin cancers, every bit it is highly metastatic and tin be hard to detect earlier it has spread to other organs. Melanomas usually appear equally asymmetrical brown and black patches with uneven borders and a raised surface (see Effigy vi.xiii). Handling typically involves surgical excision and immunotherapy.

ABCDE for Early Diagnosis

Doctors often give their patients the following ABCDE mnemonic to help with the diagnosis of early-stage melanoma. If you notice a mole on your torso displaying these signs, consult a doctor.

Asymmetry – the two sides are non symmetrical
Borders – the edges are irregular in shape
Color – the color is varied shades of dark-brown or black
Diameter – it is larger than half dozen mm (0.24 in)
Evolving – its shape has changed

Some specialists cite the post-obit boosted signs for the most serious form, nodular melanoma:

Elevated – it is raised on the skin surface
Firm – it feels hard to the bear on
Growing – information technology is getting larger

 Albinism

Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. This is primarily due to the disability of melanocytes to produce melanin. Individuals with albinism tend to announced white or very pale due to the lack of melanin in their skin and hair. Recall that melanin helps protect the pare from the harmful furnishings of UV radiation. Individuals with albinism tend to need more protection from UV radiation, as they are more prone to sunburns and pare cancer. They also tend to be more sensitive to light and have vision problems due to the lack of pigmentation on the retinal wall (Betts, et al., 2013)

Treatment of this disorder usually involves addressing the symptoms, such every bit limiting UV lite exposure to the skin and eyes. In vitiligo , the melanocytes in certain areas lose their power to produce melanin, possibly due to an autoimmune reaction. This leads to a loss of color in patches (see Figure 6.14). Neither albinism nor vitiligo direct affects the lifespan of an individual (Betts, et al., 2013)

This photo shows the back of a man's neck. There is a large, discolored patch of skin at the base of his hairline. The discolored area extends over the ears onto the cheeks, toward the front of the face. The man's head and facial hair are mostly gray, but white patches of hair are seen above the discolored skin.
Figure 6.14 Vitiligo. Individuals with vitiligo experience depigmentation that results in lighter colored patches of pare. The condition is specially noticeable on darker skin. (credit: Klaus D. Peter). From Betts, et al., 2013. Licensed under CC By iv.0.

Changes in Skin Colouration

Other changes in the advent of skin colouration can be indicative of diseases associated with other torso systems.

  • Liver disease or liver cancer can cause the accumulation of bile and the yellow pigment bilirubin, leading to the skin actualization yellow or .
  • Tumors of the pituitary gland tin result in the secretion of large amounts of melanocyte-stimulating hormone (MSH), which results in a darkening of the pare.
  • Addison'south disease tin can stimulate the release of excess amounts of adrenocorticotropic hormone (ACTH), which tin can give the peel a deep statuary colour
  • A sudden drop in oxygenation can affect skin color, causing the skin to initially turn ashen (white).
  • A prolonged reduction in oxygen levels, dark red deoxyhemoglobin becomes dominant in the blood, making the skin announced blue, a condition referred to equally . This happens when the oxygen supply is restricted, every bit when someone is experiencing difficulty in animate considering of asthma or a heart attack. However, in these cases the issue on skin color has nothing do with the pare's pigmentation (Betts, et al., 2013)

Skin Disorders

Two mutual peel disorders are eczema and acne. Eczema is an inflammatory condition and occurs in individuals of all ages. Acne involves the clogging of pores, which tin can lead to infection and inflammation, and is frequently seen in adolescents. Other disorders, include seborrheic dermatitis (on the scalp), psoriasis, fungal infections, cold sores, impetigo, scabies, hives, and warts (Betts, et al., 2013).

Eczema

Person with eczema on their forearms.
Figure six.xv Eczema. Eczema is a mutual skin disorder that presents as a cherry-red, flaky rash. (credit: "Jambula"/Wikimedia Commons). From Betts, et al., 2013. Licensed nether CC Past 4.0.

Eczema is an allergic reaction that manifests as dry, itchy patches of peel that resemble rashes (see Figure 6.15). It may be accompanied by swelling of the skin, flaking, and in astringent cases, haemorrhage. Symptoms are usually managed with moisturizers, corticosteroid creams, and immunosuppressants (Betts, et al., 2013).

Acne

The three stages of acne plugged follicle, mild inflammation and marked inflammation
Figure vi.xvi. Acne. Acne is a result of over-productive sebaceous glands, which leads to formation of blackheads and inflammation of the pare. From Betts, et al., 2013. Licensed under CC By four.0.

Acne is a peel disturbance that typically occurs on areas of the skin that are rich in sebaceous glands (face and back). It is nigh mutual along with the onset of puberty due to associated hormonal changes, just can also occur in infants and continue into adulthood. Hormones, such as androgens, stimulate the release of sebum. An overproduction and accumulation of sebum along with keratin can block hair follicles. This plug is initially white. The sebum, when oxidized by exposure to air, turns black. Acne results from infection by acne-causing bacteria (Propionibacterium and Staphylococcus), which can lead to redness and potential scarring due to the natural wound healing process (see Figure six.16) (Betts, et al., 2013).

Ringworm

Tinea or dermatophytosis is often referred to equally ringworm. Ringworm presents every bit a circular rash that is itchy and red and tin exist establish on various parts of the body. It is referred to past the location that information technology is constitute:

    • Tinea Pedis – feet or commonly referred to as athlete's feet
    • Tinea Capitis – scalp
    • Tinea barbae – bristles
    • Tinea manuum – hands
    • Tinea unguium – Toenails and fingernails also called onychomycosis
    • Tinea corporis – Trunk parts such as arms and legs (Center for Illness Command and Prevention, 2018a)

To larn more about ringworm, visit the Center for Disease Command and Prevention'south web page on fungal infections.

Psoriasis

Psoriasis is a chronic autoimmune disorder that results in patches of thick red skin with the appearance of argent scales. These patches can be institute on elbows, knees, scalp, low back, face, feet, fingernails, toenails and even the rima oris. Psoriasis tin can be confused with other skin illness then a dermatologist is the all-time doc to diagnosis psoriasis. Treatments may include creams, ointments, ultraviolet light therapy and medication (Middle for Disease Command and Prevention, 2018).  To learn more, visit the Center for Disease Control and Prevention's spider web page on psoriasis.

Injuries

Because the pare is the part of our bodies that meets the globe most directly, it is especially vulnerable to injury. Injuries include burns, wounds, equally well every bit scars and calluses. They can be caused by sharp objects, oestrus, or excessive pressure or friction to the peel (Betts, et al., 2013).

Skin injuries ready off a healing process that occurs in several overlapping stages.

  • The offset stride to repairing damaged peel is the formation of a blood clot that helps stop the catamenia of blood and scabs over with time. Many unlike types of cells are involved in wound repair, specially if the surface surface area that needs repair is extensive.
  • Before the basal stem cells of the stratum basale can recreate the epidermis, fibroblasts mobilize and divide quickly to repair the damaged tissue by collagen deposition, forming granulation tissue.
  • Blood capillaries follow the fibroblasts and help increment claret circulation and oxygen supply to the surface area.
  • Immune cells, such as macrophages, roam the expanse and engulf any foreign affair to reduce the take a chance of infection (Betts, et al., 2013).

Burns

A burn results when the skin is damaged past intense oestrus, radiation, electricity, or chemicals. The impairment results in the decease of peel cells, which can lead to a massive loss of fluid. Aridity, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Fire patients are treated with intravenous fluids to commencement , as well as nutrients that enable the trunk to repair tissues and replace lost proteins. Another serious threat to the lives of burn patients is . Burned pare is extremely susceptible to leaner and other , due to the loss of protection past intact layers of skin (Betts, et al., 2013).

Burn Classification

Burns are sometimes measured in terms of the size of the total surface area affected. This is referred to as the dominion of nines, which assembly specific anatomical areas with a pct that is a factor of nine (see Figure 6.17) (Betts, et al., 2013).

Calculating the size of a burn. Image description available.
Figure half dozen.17 Calculating the Size of a Burn down. The size of a burn will guide decisions fabricated about the demand for specialized treatment. Specific parts of the body are associated with a percentage of body surface area. From Betts, et al., 2013. Licensed under CC BY 4.0. [Epitome description.]

Burns are as well classified by the degree of their severity.

  • A first-degree burn is a superficial burn that affects only the epidermis. Although the skin may exist painful and swollen, these burns typically heal on their own within a few days. Balmy sunburn fits into the category of a first-caste burn down.
  • A 2nd-caste burn goes deeper and affects both the epidermis and a portion of the dermis. These burns event in swelling and a painful blistering of the pare. It is important to continue the fire site make clean and sterile to prevent infection. If this is done, the burn will heal within several weeks.
  • A third-degree burn fully extends into the epidermis and dermis, destroying the tissue and affecting the nerve endings and sensory function. These are serious burns that may announced white, red, or black; they require medical attention and will heal slowly without it.
  • A fourth-degree burn is fifty-fifty more severe, affecting the underlying musculus and bone.

Oddly, third and fourth-degree burns are usually not as painful because the nerve endings themselves are damaged. Full-thickness burns cannot be repaired by the trunk, considering the local tissues used for repair are damaged and require , or amputation in astringent cases, followed by grafting of the skin from an unaffected office of the torso, or from skin grown in tissue culture for grafting purposes. Skin grafts are required when the harm from trauma or infection cannot be closed with sutures or staples (Betts et al., 2013).

Scars and Keloids

Near cuts or wounds, with the exception of ones that only scratch the epidermis, lead to formation. Scarring occurs in cases in which in that location is repair of peel damage, but the skin fails to regenerate the original peel construction. Fibroblasts generate scar tissue in the form of collagen, and the bulk of repair is due to the basket-weave pattern generated by collagen fibers and does not result in regeneration of the typical cellular structure of skin. Instead, the tissue is fibrous in nature and does not allow for the regeneration of accessory structures, such as hair follicles, sweat glands, or sebaceous glands (Betts, et al., 2013).

Sometimes, at that place is an overproduction of scar tissue, considering the process of collagen formation does not cease when the wound is healed; this results in a . In dissimilarity, scars that effect from acne and chickenpox have a sunken appearance and are called atrophic scars (Betts, et al., 2013)

Scarring of pare after wound healing is a natural process and does non need to be treated further. Application of mineral oil and lotions may reduce the germination of scar tissue. Yet, modern cosmetic procedures, such equally dermabrasion, laser treatments, and filler injections have been invented as remedies for severe scarring. All of these procedures try to reorganize the construction of the epidermis and underlying collagen tissue to make information technology wait more than natural (Betts, et al., 2013).

Bedsores and Stretch Marks

Pare and its underlying tissue can be afflicted by excessive force per unit area. One example of this is called a bedsore. Bedsores, as well called decubitus ulcers, are caused by constant, long-term, unrelieved pressure on certain trunk parts that are bony, reducing blood flow to the area and leading to . Bedsores are most mutual in elderly patients who accept debilitating conditions that crusade them to be immobile. Most hospitals and long-term intendance facilities take the practice of turning the patients every few hours to prevent the incidence of bedsores. If left untreated bedsores can be fatal if they get infected (Betts, et al., 2013)

The skin can also exist affected past pressure associated with rapid growth. A stretch mark results when the dermis is stretched beyond its limits of elasticity, as the skin stretches to accommodate the excess pressure. Stretch marks commonly accompany rapid weight gain during puberty and pregnancy. They initially have a ruby-red hue, but lighten over time. Other than for cosmetic reasons, handling of stretch marks is non required. They occur most commonly over the hips and abdomen (Betts, et al., 2013).

Calluses

When you wear shoes that do not fit well and are a constant source of chafe on your toes, you tend to form a callus at the betoken of contact. This occurs because the basal stem cells in the stratum basale are triggered to divide more than often to increase the thickness of the skin at the point of abrasion to protect the rest of the torso from further harm. This is an instance of a minor or local injury, and the peel manages to react and treat the problem independent of the balance of the torso. Calluses can also form on your fingers if they are bailiwick to constant mechanical stress, such every bit long periods of writing, playing cord instruments, or video games. A corn is a specialized course of callus. Corns form from abrasions on the skin that consequence from an elliptical-type motion (Betts, et al., 2013).

Medical Terms in Context

Medical Specialties and Procedures Related to the Integumentary System

A dermatologist is a medical doctor with specialized training in treating diseases, disorders and injuries related to the integumentary organisation and its accessory structures. There are many subspecialties such equally cosmetic dermatology, and pediatric dermatology. To acquire more visit the Dermatology and Subspecialties section of the Canadian Dermatology Association website.

Dermatologists tin can exist specially trained to perform a procedure chosen Mohs surgery. Mohs surgery skin cancers in sparse layers until all cancer is removed from the tissue (Mayo Dispensary Staff, 2017).

Integumentary Organization Vocabulary

Adipocytes

Fat cells.

Adipose tissue

Fat tissue.

Autonomic nerve fibers

Unconsciously regulates communication to and from the brain.

Avascular

Without blood vessels.

Benign

Noncancerous, harmless.

Cancer

A process where abnormal cells in the body carve up uncontrollably.

Cyanosis

Abnormal condition of blue (blue colour, lips and nail beds). Typically caused by depression oxygenation.

Debridement

Excision of damaged tissue or foreign object.

Dehydration

Loss of fluids/water is greater than what is taken in.

Dermatologic

Pertaining to dermatology.

Dermatopathology

Study of diseases of the peel.

Dermis

The layer of skin that is fabricated of dumbo, irregular connective tissue that houses blood vessels, hair follicles, sweat glands, and other structures.

Epidermis

Outer layer of peel, fabricated of closely packed epithelial cells.

Excises

Remove by cut out.

Exocytosis

Active transport of molecules out of the cell.

Fascia

Gristly tissue.

Frostbite

Conservation of core torso estrus results in the peel actually freezing.

Hypodermis

Literally means below the dermis. The layer of skin below the dermis that is composed mainly of loose connective and fat tissues.

Infection

Invasion by disease-causing organisms.

Intravenous

Pertaining to within the vein.

Jaundiced

Yellowish-coloured.

Keloid

Germination of a raised or hypertrophic scar.

Keratinocytes

Cells that industry and shop the poly peptide keratin.

Meissner corpuscle

Tactile corpuscle that responds to calorie-free and impact, touch receptor.

Meissner corpuscles

Tactile corpuscle that responds to light and affect, touch receptors.

Melanocytes

Specialized cells that produce melanin which is a night pigment responsible for colouration of skin and hair.

Metastasize

Production of cells that tin can mobilize and establish tumors in other organs of the torso.

Necrosis

Tissue death.

Osteomalacia

Softening of the bones.

Pacinian corpuscle

Lamellated corpuscle that responds to vibration.

Pathogens

Disease-causing agents.

Phagocytes

Cells that engulf and blot bacteria and cell particles.

Reticulated

Net like.

Rickets

A painful condition in children where bones are misshapen due to a lack of calcium, causing bow leggedness.

Scar

Collagen-rich peel formed after the procedure of wound healing that differs from normal skin.

Stratum Basale

Deepest layer of the epidermal.

Sympathetic nervus fibers

Flying or fight response determines communication to and from the brain.

Sympathetic Nervous Organisation

Responsible for fight or flying responses.

Vascularized

Has numerous blood vessels.

Test Yourself

References

Centers for Disease Control and Prevention. (2018, October 25). Psoriasis. Centers for Illness Command and Prevention: Fungal Diseases. https://www.cdc.gov/psoriasis/

Centers for Disease Command and Prevention. (2018a, Baronial vi). Ringworm.  Centers for Disease Control and Prevention: Fungal Diseases.  https://world wide web.cdc.gov/fungal/diseases/ringworm/definition.html

CrashCourse. (2015, January 6). The Integumentary system, function 1 – skin deep: Crash Course A&P #6 [Video]. YouTube. https://youtu.be/Orumw-PyNjw

CrashCourse. (2015, February 16). The Integumentary arrangement, part 2 – pare deeper: Crash Course A&P #7 [Video]. YouTube. https://youtu.be/EN-10-zXXVwQ

Mayo Dispensary Staff. (2017, September half dozen). Mohs surgery. Mayo Clinic. https://www.mayoclinic.org/tests-procedures/mohs-surgery/most/pac-20385222#:~:text=Mohs%20surgery%20is%20a%20precise,known%20as%20Mohs%20micrographic%20surgery.

Image Descriptions

Figure 6.1 image description: This illustration shows a cross section of skin tissue. The outermost layer is called the epidermis, and occupies one 5th of the cantankerous section. Several hairs are emerging from the surface. The epidermis dives effectually one of the hairs, forming a follicle. The middle layer is called the dermis, which occupies iv fifths of the cantankerous section. The dermis contains an erector pilli muscle continued to one of the follicles. The dermis also contains an eccrine sweat gland, composed of a agglomeration of tubules. One tubule travels upwardly from the bunch, through the epidermis, opening onto the surface a pore. In that location are two string-like nerves travelling vertically through the dermis. The right nervus is attached to a Pacinian corpuscle, which is a xanthous structure consisting of concentric ovals similar to an onion. The lowest level of the skin, the hypodermis, contains fatty tissue, arteries, and veins. Blood vessels travel from the hypodermis and connect to hair follicles and erector pilli musculus in the dermis. [Return to Figure 6.1].

Figure 6.2 image description: Function A is a micrograph showing a cross department of thin skin. The topmost layer is a thin, translucent layer with irregular texture and areas where cells are sloughing off. The deepest layer is dark purple and extends into the third layer with finger like projections. The third low-cal imperial layer contains sparse bands of fibers and small-scale, dark cells. The quaternary, and deepest layer, is darker than the third layer, but is even so low-cal purple. It contains thick fiber bands that are loosely packed. Part B is a magnified view of the epidermis of thick pare. Information technology shows the topmost layer is five times thicker than the topmost layer of thin skin. The topmost layer of thick peel is also denser and less translucent than the topmost layer of thin skin. [Return to Effigy vi.2].

Figure 6.3 image description: The outer layer of cells in this micrograph is the thinnest layer and stained deep regal due to total keratinization of dead cells. The next layer occupies one quarter of the micrograph, is lightly stained, and is a dense drove of cells. The third layer from the tiptop is mostly white, with lightly stained, loosely-packed strands radiating in random directions. The bottom-about layer is densely-packed, with thick bands of highly organized muscle tissue that are darkly stained. [Return to Figure six.3].

Figure half dozen.4 image description: This micrograph shows layers of peel in a cross section. The papillary layer of the dermis extends between the downward fingers of the darkly stained epidermis. The papillary layer appears finer than the reticular layer, consisting of smaller, densely-packed fibers. The reticular layer is three times thicker than the papillary layer and contains larger, thicker fibers. The fibers seem more loosely packed than those of the papillary layer, with some separated by empty spaces. Both layers of the dermis contain cells with darkly stained nuclei. [Return to Figure half-dozen.iv].

Figure vi.5 paradigm description: Role A is a photo of a homo skiing with several snow-covered trees in the background. Part B is a diagram with a right and left one-half. The left half is titled " Heat is retained past the body," while the right half is titled "Rut loss through radiation and convection." Both evidence claret flowing from an artery through 3 capillary beds inside the skin. The beds are arranged vertically, with the topmost bed located forth the boundary of the dermis and epidermis. The bottommost bed is located deep in the hypodermis. The middle bed is evenly spaced betwixt the topmost and bottommost beds. In each bed, oxygenated claret (red) enters the bed on the left and deoxygenated blood (blue) leaves the bed on the right. The left diagram shows a picture of snowflakes in a higher place the capillary beds, indicating that the weather is cold. Blood is only flowing through the deepest of the iii capillary beds, as the upper beds are closed off to reduce heat loss from the outer layers of the peel. The correct diagram shows a moving-picture show of the sun above the capillary beds, indicating that the weather is hot. Blood is flowing through all 3 capillary beds, allowing oestrus to radiate out of the claret, increasing estrus loss. Part C is a photograph of a man running through a forested trail on a summer twenty-four hour period. [Return to Figure 6.v].

Effigy 6.six image description: A cross department of the peel containing a hair follicle. The follicle is teardrop shaped. Its enlarged base of operations, labeled the hair seedling, is embedded in the hypodermis. The outermost layer of the follicle is the epidermis, which invaginates from the peel surface to envelope the follicle. Inside the epidermis is the outer root sheath, which is just present on the hair bulb. It does not extend up the shaft of the hair. Within the outer root sheath is the inner root sheath. The inner root sheath extends about half of the way up the hair shaft, ending midway through the dermis. The hair matrix is the innermost layer. The hair matrix surrounds the bottom of the hair shaft where it is embedded inside the pilus bulb. The hair shaft, in itself, contains iii layers: the outermost cuticle, a middle layer chosen the cortex, and an innermost layer chosen the medulla. [Render to Effigy 6.6].

Figure 6.7 image clarification: The anatomy of the fingernail region. The top image shows a dorsal view of a finger. The proximal nail fold is the office underneath where the pare of the finger connects with the edge of the nail. The eponychium is a thin, pink layer between the white proximal border of the smash (the lunula), and the edge of the finger skin. The lunula appears as a crescent-shaped white area at the proximal edge of the pinkish-shaded nail. The lateral smash folds are where the sides of the boom contact the finger peel. The distal edge of the nail is white and is called the free edge. An arrow indicates that the nail grows distally out from the proximal blast fold. The lower image shows a lateral view of the boom bed beefcake. In this view, i can encounter how the border of the nail is located just proximal to the boom fold. This end of the nail, from which the smash grows, is chosen the boom root. [Render to Figure 6.7].

Effigy 6.8 paradigm description: An analogy of an eccrine sweat gland embedded in a cross department of skin tissue. The eccrine sweat gland is a package of white tubes embedded in the dermis. A unmarried white tube travels upwardly from the packet and opens on to the surface of the epidermis. The opening is called a pore. At that place are several pores on the small block of peel portrayed in this diagram. [Return to Figure 6.8].

Figure 6.9 image description: This figure consists of two photos. One photo shows a young woman on the phone. Her skin is polish and unwrinkled. The other photo shows an elderly women in the same posture while on the telephone. The peel of her hands and forearms is wrinkled. [Return to Effigy six.9].

Figure 16.10 image description: Five photos of moles. The three upper photos show moles that are pocket-size, flat, and night chocolate-brown. The bottom left photo shows a dark blackness mole that is raised above the skin. The bottom right photo shows a big, raised, ruddy mole with protruding hairs. [Return to Effigy 6.10].

Effigy sixteen.17 paradigm description: This diagram depicts the per centum of the total body expanse burned when a victim suffers complete burns to regions of the body. Complete burning of the face, head and neck business relationship for 19% of the full trunk surface area. Called-for of the chest, abdomen and entire back above the waist accounts for 36% of the total body area. Anterior and posterior surfaces of the arms and hands account for xviii% of the total body surface area (ix% for each arm). The anterior and posterior surface of both legs, along with the buttocks, accounts for 36% of the total body area (18% for each leg). Finally, the inductive and posterior surfaces of the genitalia business relationship for 1% of the full body expanse. [Return to Figure vi.17].

Unless otherwise indicated, this chapter contains material adapted from Anatomy and Physiology (on OpenStax), by Betts, et al. and is used under a a CC BY 4.0 international license. Download and access this book for free at https://openstax.org/books/anatomy-and-physiology/pages/one-introduction.

Source: https://ecampusontario.pressbooks.pub/medicalterminology/chapter/integumentary-system/

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